1-tert-butyl 3-methyl 3-fluoropyrrolidine-1,3-dicarboxylate - Names and Identifiers
1-tert-butyl 3-methyl 3-fluoropyrrolidine-1,3-dicarboxylate - Physico-chemical Properties
Molecular Formula | C11H18FNO4
|
Molar Mass | 247.27 |
Density | 1.17±0.1 g/cm3(Predicted) |
Boling Point | 283.2±40.0 °C(Predicted) |
pKa | -4.98±0.40(Predicted) |
Storage Condition | 2-8°C |
1-tert-butyl 3-methyl 3-fluoropyrrolidine-1,3-dicarboxylate - Introduction
1-tert-butyl 3-methyl 3-fluoropyrrolidine-1,3-dicarboxylate is a pharmaceutical intermediate and an organic compound. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless or light yellow oily liquid.
-Molecular formula: C10H15NO4F.
-Molecular weight: 239.23g/mol.
-Melting point:-35 ° C.
-Boiling point: 280 ° C (decomposition).
-Density: 1.222g/cm³.
-Solubility: Soluble in organic solvents such as ethanol and methanol, insoluble in water.
Use:
- 1-tert-butyl 3-methyl 3-fluoropyrrolidine-1,3-dicarboxylate is commonly used as an intermediate in the fields of medicine, pesticide and dye.
-It can be used for multiple important organic synthesis reactions to prepare various organic compounds.
Method:
The preparation method of-1-tert-butyl 3-methyl 3-fluoropyrrolidine-1,3-dicarboxylate is relatively complicated, and generally requires a multi-step reaction.
-The commonly used preparation method is to react 3-fluoropyrrolidine with tert-butyl Formic Anhydride to obtain an intermediate product, and then react with trimethylammonium bromide to obtain the final product.
Safety Information:
- 1-tert-butyl 3-methyl 3-fluoropyrrolidine-1,3-dicarboxylate is an organic compound and care should be taken to prevent contact with skin, eyes and inhalation.
-Wear protective gloves, goggles and protective masks during use or handling.
-Avoid contact with oxidants and strong acids during storage and handling.
-In the use of the process should strictly abide by the relevant safety procedures, such as well-ventilated laboratory conditions.
-For accidental exposure or inhalation, seek timely medical attention and bring the compound's safety data sheet.
Last Update:2024-04-09 02:00:52